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Synucleinopathies (also called α-Synucleinopathies) are neurodegenerative diseases characterised by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells.
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Synucleinopathies are a group of neurodegenerative diseases characterized by abnormal deposition of α-synuclein, and include Parkinson's disease (PD), dementia ...
The synucleinopathies are a diverse group of neurodegenerative disorders that share a common pathologic lesion composed of aggregates of insoluble.
Dec 18, 2021 · Synucleinopathies are a group of neurodegenerative disorders characterized by neuronal or glial inclusions, or both, composed of aggregated α- ...
A neurodegenerative disorder displaying an altered α-synuclein (αS) in the brain tissue is called α-synucleinopathy (αS-pathy) and incorporates clinical ...
Mar 1, 2023 · Abnormal forms of α-syn trigger selective and progressive neuronal death through mitochondrial impairment, lysosomal dysfunction, and alteration of calcium ...
Synucleinopathies are a subgroup of neurodegenerative diseases, characterised by impairment of alpha-synuclein (αSyn) metabolism, producing abnormal ...
The synucleinopathies refer to a group of disorders characterized by abnormally misfolded α-synuclein aggregates in the peripheral and central nervous systems.
May 29, 2023 · Synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA), are neurodegenerative ...
Mar 20, 2024 · A group of neurodegenerative disorders collectively known as synucleinopathies are characterized by the deposition of phosphorylated α-synuclein ...